Drug Description for Darunavir

Product Name:

Darunavir

Other Names:

• Prezista (brand name)

Active Ingredient:

• Darunavir

Use:

Darunavir is an antiretroviral medication used to treat HIV-1 infection. It is a protease inhibitor that works by inhibiting the action of the HIV-1 protease enzyme, which is crucial for the virus's replication. When used in combination with other antiretroviral agents, Darunavir helps to decrease the amount of HIV in the blood, maintaining a low viral load and boosting the immune system.

Recommended Dosage:

• Adult Dosage: 800 mg taken once daily with 100 mg of ritonavir or 150 mg of cobicistat as a booster.

• Pediatric Dosage: Dosage is based on body weight and must be determined by a healthcare provider.

Directions:

• Take Darunavir exactly as prescribed by your healthcare provider.

• It must be taken with food to enhance absorption.

• Swallow the tablets whole with a full glass of water.

• Always take Darunavir in combination with a booster (ritonavir or cobicistat) and other antiretroviral medications.

• Do not miss doses or stop taking Darunavir without consulting your healthcare provider, as this can lead to drug resistance.

Cautions:

• Inform your healthcare provider of any allergies or medical conditions, especially liver disease, diabetes, or hemophilia.

• Notify your healthcare provider of all medications you are currently taking to avoid potential drug interactions, especially other antiretroviral medications, anticoagulants, and medications for other chronic conditions.

• Darunavir can cause liver problems; regular liver function tests are recommended.

• Avoid consuming alcohol while taking Darunavir, as it can increase the risk of liver problems.

• Pregnant or breastfeeding women should consult their healthcare provider before using this medication.

Guidelines:

• Regularly monitor your viral load and CD4 counts as directed by your healthcare provider.

• Adhere to a healthy lifestyle, including a balanced diet and regular exercise, to support your overall health and treatment regimen.

• Store Darunavir at room temperature, away from moisture and heat. Keep it out of reach of children.

FAQs:

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Q: Can Darunavir cure HIV?

A: Darunavir is not a cure for HIV, but it helps manage the infection by lowering the viral load in the blood. Consistent use can improve the quality of life and reduce the risk of HIV-related complications.

Q: Are there any common side effects?

A: Common side effects include diarrhea, nausea, rash, headache, and abdominal pain. Contact your healthcare provider if these effects persist or worsen.

Q: Can I take other medications while using Darunavir? A: Some medications can interact with Darunavir, potentially decreasing its effectiveness or increasing side effects. Always inform your healthcare provider about all the medications and supplements you are taking.

Q: Is Darunavir safe during pregnancy?

A: The safety of Darunavir during pregnancy is not well established. If you are pregnant or planning to become pregnant, consult your healthcare provider to weigh the potential benefits and risks.

Q: How should I store Darunavir?

A: Store Darunavir at room temperature, away from moisture and heat. Keep it out of reach of children.

Q: Can I drive while taking Darunavir?

A: Darunavir is not known to affect your ability to drive. However, if you experience side effects such as dizziness, use caution when driving or operating machinery.

Q: How long do I need to take Darunavir?

A: Darunavir is part of a long-term treatment plan for managing HIV. You will likely need to take it for as long as your healthcare provider recommends.

Q: What if I experience severe side effects?

A: If you experience severe side effects such as severe rash, liver problems, or signs of an allergic reaction, seek medical attention immediately.

By following these guidelines and using Darunavir as prescribed, you can effectively manage your HIV infection and maintain your health. Always consult your healthcare provider for personalized advice and information.